We will try in this part of understand why the HIFUtherapie, which uses high intensity focused ultrasound is an effective technique to get a real "lift effect" without surgery
The primary step in the process leading to the lift effect is the process of denaturation of collagen targeted by focused ultrasound which induces focused microlesions.
These extremely accurate microlesions induce in turn a tissue repair with the synthesis of new collagen, this time from premium involved in remodeling the SMAS as well as the deep DermIS attending the effect overall lift that can be observed immediately after a procedure by HIFU therapy, which is not that continue to improve with time and this , until one year after the procedure.
Following the steps in the functioning of focused ultrasound:
First step: denaturation of collagen
When a complete facial treatment is performed by HIFU, is close to 16 000 if points that are performed with a depth and energy issued during each impact well defined
From a chemical standpoint, ultrasound emitted during each shot induce vibration of molecules that make up the target tissue collagen which will result in heat.
Thus at the level of the focal point (where all the emitted ultrasonic beams converge) the temperature is between 60 ° and 70 °
This level of heating is very important to achieve because it is from this temperature the collagen begins to denature and lose its original artchitecture: this phenomenon is called collagen denaturing process.
Various scientific studies have demonstrated that the collagen fibres that reach a temperature given for awhile, tend to shorten. At the molecular level, this phenomenon can be explained by a break in the bridges formed by hydrogen atoms that make up the collagen from 58 ° C. It is also at this temperature which can be observed a synthesis of new collagen.
It is this – almost instantaneous – shortening that explains why there is some patients a beginning of the effect of the face and neck lift, just after a meeting of Hifutherapie
Other studies with several hundred patients, it allowed to highlight that the temperature of heating was high and over denaturation of the collagen fibres was intense at the level of each coagulation performed and this point within two minutes that followed each shot
This partly explains why it is so important to reach an optimal temperature during HIFU therapy which allows to obtain the desired effect on the targeted tissues leading to the synthesis of new collagen, better quality, that will replace the previous.
Just after a procedure, can also observe an improvement in the quality of the skin that is due to the redness and skin edema that can be observed at the level of the areas worked during the meeting which are mainly due to inflammatory fluid accumulation in treated tissues.
This inflammatory fluid is secreted after coagulation items made in targeted deep tissue. The latter will somehow "fill" originally the skin wrinkles and participates in the sensation that can have the patient's 'new skin' immediately after a procedure.
Second step: synthesis of new collagen and collagen remodeling existing
During a session of HIFU, micro coagulation points, performed under the skin are equivalent to micro-wounds to the body. These induce a tissue self-healing process that triggers:
- A synthesis of new collagen of better quality than the already present collagen
- A complete reorganization of the existing collagen, which becomes more elastic and much more compact
These changes in coagulation points will grow over time, up to 6 months, even a year after the procedure leading to a tensor effect and "lift up" treated tissue
Three separate processes will allow for this phenomenon:
1 – The inflammation induced by HIFUtherapie
The inflammatory response can be observed up to 10 weeks after the treatment.
During this phase, the immune system cells called Macrophages will flow in the heart of every point of coagulation and will play an important role in digestion and the elimination of damaged tissues.
These macrophages will also release molecules of cellular signals, called cytokines that will attract the fibroblasts which will in turn produce new collagen.
On the other hand, it seems according to some experts that the presence of healthy tissue between each point of coagulation is essential for the repair process is performed properly.
2 – The proliferation
It is the process which directly follows the inflammation.
During the stage of proliferation fibroblasts are going to make
- A new collagen (of type III), more resistant
- Elastin that can restore skin elasticity
- Fibronectin, proteoglycans and proteases involved in skin support
Some studies were able to highlight at the days 28th an increased presence of fibroblasts in the DermIS level after warming has been induced at the level of the treated area, which means clearly that an active skin resurfacing is underway.
A significant increase of elastin is also highlighted. This has been demonstrated by studies that have measured a collagen levels increased by 23.7% on skin treated by HIFU therapy with an overlying epidermis of much better quality with elastin fibers much better organized than they were prior to treatment being thicker and more parallel to the level of the dermis.
3 – Remodeling
The process of collagen remodeling is a crucial step to achieve a good result in the lift effect sought to achieve with HIFU therapy
This phase starts generally 3 weeks after treatment and can last up to a year. It was during this time that new collagen type 1 replaces type 3 collagen which was targeted during the meeting.
Studies have shown that collagen type 1 continued to be produced, even a year after treatment.
The process of remodeling, protein HSP47-driven leads to a complete replacement of the coagulated area by new collagen approximately 10 weeks after the treatment.
It depends on the patient's skin condition and will obviously less effective if the latter presents an important release
The Hifutherapie is currently the only technology on the market of the aesthetic medicine which allows to obtain so effectively in the fight against sagging skin. It allows to reach a real effect lifting without surgery or scalpel and can also be performed on all skin types to any it period of the year.
By heating the tissues deep consistently, it allows to obtain a denaturation of collagen which restructures subsequently helped by the production of collagen "brand new" via fibroblasts.
The HIFU gives excellent results that didn't go that improves with time, making it an excellent alternative to surgical facelifts when sagging skin is not too important